急性乌头碱中毒致心律失常联合使用阿托品及抗心律失常药物可提供抢救成功效率

Atropine combined with antiarrhythmic drugs can increase rescue success rate in patients with arrhythmia induced by acute aconite poisoning

目的对急性乌头碱中毒致心律失常联合使用阿托品及抗心律失常药物可提供抢救成功效率进行探讨。方法随机抽取我院在2011年1月-2013年12月治疗的50例急性乌头碱中毒致心律失常患者,通过回顾性分析对患者的临床资料进行分析。结果 50例患者中31例患者的心电图显示快速性心律失常,其中2例患者属于致命性心律失常,19例患者属于缓慢性心律失常。在经过我院使用盐酸戊乙奎醚、阿托品等药物进行治疗后,50例患者均已好转或者是痊愈出院。结论急性乌头碱中毒会导致患者出现心律失常,严重时会威胁到患者的生命安全。如果在早期使用盐酸戊乙奎醚、阿托品等抗胆碱能药物进行及时治疗的话,可有效挽救患者的生命。必要时,也可有选择性的使用利多卡因等药物进行治疗,以提高急性乌头碱中毒致心律失常患者的抢救成功效率。

Objective To investigate the rescue success rate in patients with arrhythmia induced by acute aconite poisoning and treated with atropine and antiarrhythmic drugs. Methods Fifty patients with arrhythmia induced by acute aconite poisoning and treated in our hospital between January 2011 and December 2013 were randomly sampled, and their clinical data were retrospectively analyzed. Results As shown by ECG, among the 50 patients, 31 patients had tachyarrhythmia and the other 19 had bradyarrhythmia; among the 31 patients with tachyarrhythmia, 2 had fatal arrhythmia. After treatment with penehyclidine hydrochloride, atropine, and so on, all the 50 patients were improved or cured and discharged. Conclusion Acute aconite poisoning can induce arrhythmia and even is life-threatening when severe; while early use of anticholinergic agents such as atropine and penehyclidine hydrochloride can save the lives of patients, and lidocaine and other drugs can be selectively used to increase the rescue success rate in patients with arrhythmia induced by acute aconite poisoning.