甲壳类水产品主要过敏原致敏反应及免疫调控机制

Molecular Mechanisms on Sensitization and Immune Regulation of Major Allergens from Crustaceans

甲壳类动物作为水产品中的1类,其市场和消费群体不断扩大。由甲壳类水产品引发的食物过敏日益增多。本文简要介绍了甲壳类水产品过敏蛋白的种类、结构及鉴定方法,并对其致敏反应机理及免疫调控分子机制进行了重点阐述。

The growing international trade in crustacean seafood products has enhanced the popularity and frequency of consumption across many countries. The increased production and consumption of crustacean seafood has been accompanied by more frequent reports of adverse health problems especially referred to allergy. In this review, the structure and identification methods of different allergic proteins in crustaceans are introduced. Moreover, the molecular mechanisms on allergic response and immune regulation of major allergens from crustaceans are mainly elucidated.