原发性肠道恶性淋巴瘤临床分析

Clinical analysis of primary intestinal malignant lymphoma

目的探讨原发性肠道恶性淋巴瘤的临床特点、诊断和治疗。方法回顾本院12年中收治14例肠道原发性恶性淋巴瘤临床资料。结果该病有较明显临床特点,好发于小肠,尤其回肠多见,常表现为腹泻和便血,不明原由的反复高热,用抗生素治疗无效,易发生肠套叠或肠梗阻,放射学检查肠壁有动脉瘤样改变。对其治疗原则是争取原发灶根治切除。根治切除困难时亦做姑息性切除,再辅助化疗、放疗,以提高患者远期生存力。结论肠道恶性淋巴瘤有较典型临床表现,只要重视考虑全面,诊断治疗不十分困难。

Objective To explore the clinical manifestation, diagnosis and treatment of primary intestinal malignant lymphoma.Methods Retrospectively analyzed clinical data of 14 patients with primary intestinal malignant lymphoma during the past 12 years in our hospital.Results The disease had obvious clinical manifestation, for example, it is commonly located in small intestine especially ileum; often with diarrhea and stool blood; unidentified coming and going high fever, and could not be controlled by antibiotics; intussusceptions or intestinal obstruction often be found among those cases; radiography check shaves aneurysm-like change in the intestinal wall. Performed palliative resection when radical resection was difficult, in adjuvant chemotherapy and radiotherapy, in order to improve the patients’ long-term viability.Conclusion With the relatively typical clinical manifestation, diagnosis and treatment are not so difficult if the disease were emphasize from every aspect.