新疆伊犁地区人群中幽门螺杆菌感染状况的调查与分析

The Investigation and Analysis of the Helicobacter Pylori Infection Status in the Population of Yili Area,Xinjiang

为了解新疆伊犁地区有消化道症状患者幽门螺杆菌(下面简称Hp)的感染状况及危险因素,为防治工作提供一定的理论基础。采用组织学美蓝染色检测和13C或14C尿素呼气试验相结合的方法对2002年-2012年期间来伊犁州友谊医院就诊的消化道疾病患者31613例进行Hp的检测,并分析性别、年龄、族别、生活环境、经济收入等因素与Hp感染的相关关系。结果显示,伊犁地区人群Hp感染率为53.4%,(其中组织学检测法Hp感染率为51.3%(16217/31613),14C呼气试验检测法感染率为51.0%(16125/31613));男性感染率与女性感染率相当(53.9%Vs52.9%P=0.07),无统计学差异。不同年龄段的人群Hp感染率不同,随着年龄的增长基本呈上升趋势,60岁之后感染率开始下降。维吾尔族Hp感染率为55.0%(1954/3553),哈萨克族56.4%(2617/4640),汉族52.6%(12311/23420),汉族与维吾尔族,汉族与哈萨克族之间的差异均有统计学意义,而维吾尔族和哈萨克族的感染率无统计学差异。由此可知,新疆伊犁地区人群Hp感染率低于全国平均水平。年龄、族别、生活环境、经济收入、饮用水源、餐具消洗等是影响Hp感染的因素,Hp感染与性别、吸烟、饮酒、饲养动物无关。

To investigate and analysis of the infection status of helicobacter pylori（Hp） in the population who suffered from the digestive system disease in Yili area of Xinjiang,and to provide evidence for the prevention and the treatment of Hp in this region.Two methods（histological test and13C or14C-urea breath test） were employed to detect the infection situation in 31613 people in Yi li Youyi hospital from 2002 to 2012.The information of sex,age,race,living condition and income was also collected to do the correlation analysis with Hp infection.As the result showed that the total Hp infection rate was 53.4%,（the histological test was 51.3%;and the urea breath test was 51.0%） and 53.9% in the males,equal to the females（52.9%,P =0.07）.There was a connection between age and Hp infection,which suggested that the infection rate increased with age.However,the infection rate began to decrease when people reached to 60 years.Hp infection rate of Uyghur was 55.0%（1954/3553）,Kazak 56.4%（2617/4640）,Han 52.6%（12311/23420）;the difference between Han and Uyghur, and that between Han and Kazak was statistically significant.Yet Uyghur and Kazak had no statistically significant. Total Hp infection rate of Yili is lower than the average level in China.Age,race,living condition,income,drinking and dinnerware washing is related to Hp infection,whereas,Hp infection has no relation with sex,smoking, drinking, and animals raising.