脑小血管病病理生理机制研究进展

Research Progress in Pathophysiological Mechanism of Cerebral Small Vessel Disease

脑小血管病(cerebral small vessel disease,CSVD)是由于不同原因的脑小血管或微小血管发生病理改变后导致的疾病,是临床上引起血管性认知功能障碍(vascular cognitive impairment,VCI)的重要病因。充分认识CSVD的发生、发展,将为预防VCI提供可能。本文从脑小血管病的病理生理机制的研究进展进行综述,以期为临床实践提供思路。

Cerebral small vessel disease （CSVD） is such a kind of disease caused by pathological changes of cerebral small vessel or the tiny blood vessels due to different factors, it is a clinically important cause of vascular cognitive impairment （VCI）. Full awareness of the occurrence and development of CSVD will provide possiblility for prevention of VCI. This article reviews research progress of the pathophysiological mechanism of CSVD so as to provide ideas for clinical practice.