摘要
目的:为促进万古霉素的合理使用提供参考。方法:回顾性调查某院2011年6月-2014年5月期间使用万古霉素的全部住院病历,对药品使用及病原学检查情况进行汇总,并根据所制定的万古霉素临床应用合理性评估标准进行用药合理性评估,对不适宜问题进行分类统计分析。结果:共抽取使用万古霉素的病历328份。万古霉素药物利用指数(DUI)为0.89;微生物送检率为94.8%,按药敏试验结果选择用药率为59.5%;用药不适宜病例共45例(占全部调查病例的13.7%),其中用法用量不适宜(21例,占6.4%)和溶媒使用不适宜(15例,占4.6%)为主要问题。结论:该院万古霉素不存在过度使用现象,微生物送检情况达标,但临床使用中仍存在某些不适宜问题。开展万古霉素临床应用合理性评估有助于发现典型问题,为合理用药干预及持续改进提供参考。
OBJECTIVE： To provide references for rational use of vancomycin. METHODS ： All the medical records of inpatients treated with vancomycin from Jun. 2011 to May 2014 were extracted retrospectively. The utilization and microbiological test of vancomycin were investigated. By setting the vancomycin evaluating standard, the medication rationality of vancomycin was evaluated and inappropriate cases were classified and analyzed statistically. RESULTS： There were 328 medical records of vancomytin. DUI of vancomycin was 0.89; the rate of microbial inspection was 94.8% and the rate of choosing vancomycin according to the drug sensitive test result was 59.5%. There were 45 cases of irrational use of vancomycin （13.7%） ; irrational usage and dosage （21 cases, 6.4% ） and unsuitable solvent selection （15 cases, 4.6% ） were major problems. CONCLUSIONS： The overuse of vancomycin phenomenon doesn＇t exist and the microbial inspection rate is qualified in the hospital. There are some problems as inappropriate use of vancomycin. The rationality evaluation of vancomycin use is helpful to discover typical medication problems, which is supposed to provide scientific evidence for intervention and continuous improvement of rational medication.
出处
《中国药房》
CAS
CSCD
2014年第32期2991-2994,共4页
China Pharmacy
基金
首都医学发展科研基金项目(No.2011-管-23)
