江苏省2007-2012年流行性乙型脑炎流行病学特征分析

Analysis on epidemiology of Japanese type B encephalitis in Jiangsu Province,2007-2012

目的分析江苏省流行性乙型脑炎（epidemic encephalitis B）即日本乙型脑炎（Japanese type B ellcephalitis，简称乙脑）的流行特征。方法用SPSS18．0和Excel2010软件分析江苏省2007—2012年乙脑疫情信息，采用酶联免疫吸附测定（enzyme-linked immunosorbent assay，ELISA）方法检测病例血液或脑脊液乙脑病毒IgM抗体。结果2007—2012年，年均发病率为0．06／10万，年均病死率为6．41％。连云港市、宿迁市和苏州市为高发市，其发病数占总病例的54．80％。7、8月为发病高峰，占93．59％。全省发病主要集中在0～14岁儿童，占94．66％；以散居儿童为主，占55．87％。全程接种乙脑疫苗的占19．22％，非全程接种占13．52％，无接种和接种史不详者合计占60．85％。实验室确诊病例占88．26％。结论江苏省乙脑病例的分布呈现季节性、地域性和人群差异的特点。

Objective To analyze the epidemiologic characters of Japanese type B encephalitis （JE） in Jiangsu Province. Methods The epidemic situation information of JE cases from 2007 to 2012 was analyzed by SPSS 18.0 and Excel 2010. And JE IgM antibody in sera or cerebrospinal fluids of the cases was tested by ELISA. Results During 2007 - 2012, the annual average incidence of Japanese type B encephalitis and the annual average mortality were 0. 06/100 000 and 6.41%. Cases were distributed mainly in Lianyungang, Suqian and Suzhou Cities, which accounting for 54. 80% of the total. The peak months were July and August, accounting for 93.59% of all the cases. Most cases were in the age of 0- 14 years （94. 66% ） and were scattered children（55.87% ）. 39. 15% of the JE cases were vaccinated but 13.52% of them did not complete the whole course. 60. 85% of the cases did not know the experience of vaccination. 88.26% of the JE cases were confirmed through laboratory tests. Conclusions The distribution of JE cases shows seasonal, regional characteristics and crowd differences in Jiangsu Province.