小花棘豆中毒对家兔脏器指标的影响

Effects of Oxytropis glabra DC Poisoning on Organ Index of Rabbits

为探讨小花棘豆(Oxytropis glabra DC)对家兔脏器指标的影响,试验挑选健康22只,分为两组,其中,试验组12只[按照10 g/(d·kg体重)的剂量饲喂小花棘豆干粉];对照组10只(饲喂青干草和少量精料),试验期为70 d,试验结束后取其脏器,计算脏器指数。结果显示,与正常对照相比,试验组家兔脑指数、肝脏指数、肾脏指数、肾上腺指数、睾丸指数、卵巢指数和肺脏指数增大,心脏指数、脾脏指数和胰脏指数下降,部分指标差异达到显著或极显著(P<0.05或P<0.01),与小花棘豆中毒相关性最强的指标为脑指数;但小花棘豆中毒对家兔胃肠道指标无明显影响。结果表明,小花棘豆中毒导致家兔肝、肾、脑等实质性器官损伤。

To investigate the effects of oxygen parameters of Oxytropis glabra DC poisoning on rabbits, 22 rabbits were divid-ed into control group （10 rabbits） and test group （12 rabbits）. The dried plant of the O. glabra DC was comminnuted, and the test group was fed with O. glabra DC at 10 g/kg everyday respectively during the test period, and the control group was fed with hay and concentrate. After 70 day toxicity test, their organs were drawn and the quots of organ were calculated. The results showed that the index of brain, liver, kidney, adrenal, testicle, ovary and lung in the poisoned rabbits were higher than those of normal control group, while the index of heart, spleen and pancreas in the poisoned rabbits were lower than those of normal control group. Partial index showed significant or extremely significant differences between the two groups （P〈0.05 or P〈0.01）. The brain index presented strong relationship with O. glabra DC poisoning. But O. glabra DC showed no significant effects on gastrointestinal tract parameters in rabbits. It indicated that O. glabra DC poisoning could cause parenchymatous organ injury of rabbits such as liver, kidney and brain.