合成毒品滥用人群中乙型肝炎病毒的感染状况和影响因素分析

HEPATITIS B VIRUS INFECTION AND RISK FACTOR AMONG SYNTHETIC DRUG USERS

目的:了解合成毒品滥用人群一般人口学特征、行为特征与乙型肝炎病毒(Hepatitis B Virus,HBV)感染的关系,分析该人群HBV感染的影响因素。方法:调查广州市某戒毒所合成毒品滥用者的一般人口学特征和行为特征,用酶联免疫吸附试验(ELISA)检测HBV血清标志物,对数据采用单因素和多因素统计分析。结果:合成毒品滥用人群HBV感染率为75.46%,HBV感染与滥用年限呈正相关。结论:合成毒品滥用人群是高HBV感染率人群,其增加了HBV传播的风险。

Objective ： To investigate the relationship between general demographic characteristics, behavior characteristics of synthetic drug users and HBV infection, to explore the risk factor of HBV infection and transmission among the synthetic drug users. Methods： The general demographic characteristics and behavior characteristics of the synthetic drug users were investigated in a Guangzhou compulsory isolation detoxification center, the HBV serum markers were detected by enzyme -linked immunosorbent assay （ELISA）, and the univariate and multiple logistic regression were used for statistical analysis. Results： HBV infection rate is 75.46% in the synthetic drug users, HBV infection is positively correlated with years of abuse. Conclusion The synthetic drug users has a high HBV infection prevalence, which increases the risk of HBV transmission.