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Predictors and outcomes of photodynamic therapy on circumscribed choroidal hemangiomas in Chinese patients

Predictors and outcomes of photodynamic therapy on circumscribed choroidal hemangiomas in Chinese patients
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摘要 Choroidal hemangiomas (CHs) are relatively rare,benign,vascular,hamartomatous tumors.They are categorized to circumscribed choroidal hemangiomas (CCHs) or diffuse choroidal hemangiomas (DCHs) clinically and histologically.Although circumscribed CHs (CCHs) are often asymptomatic,they can affect visual acuity (VA) if they are situated beneath the fovea,where they can cause accumulation of secondary subretinal fluid and/or cystic retinal degeneration.Due to its minimal invasiveness and negligible toxicity to the normal retina,photodynamic therapy (PDT) with verteporfin has been applied widely in the treatment of CCH.1 Treatment strategies for CCHs should take into account tumor size,anatomic location,VA,and presence/absence of complications.The present study was conducted to identify potential predictors of successful PDT treatment other than those previously reported.We also present alternative treatment modalities for larger,more complicated CCHs.Keywords:circumscribed choroidalhemangiomas; photodynamic therapy; tumor height; predictors and outcomes;success rate;fluorescence angiography; indocyanine green angiography Choroidal hemangiomas (CHs) are relatively rare,benign,vascular,hamartomatous tumors.They are categorized to circumscribed choroidal hemangiomas (CCHs) or diffuse choroidal hemangiomas (DCHs) clinically and histologically.Although circumscribed CHs (CCHs) are often asymptomatic,they can affect visual acuity (VA) if they are situated beneath the fovea,where they can cause accumulation of secondary subretinal fluid and/or cystic retinal degeneration.Due to its minimal invasiveness and negligible toxicity to the normal retina,photodynamic therapy (PDT) with verteporfin has been applied widely in the treatment of CCH.1 Treatment strategies for CCHs should take into account tumor size,anatomic location,VA,and presence/absence of complications.The present study was conducted to identify potential predictors of successful PDT treatment other than those previously reported.We also present alternative treatment modalities for larger,more complicated CCHs.Keywords:circumscribed choroidalhemangiomas; photodynamic therapy; tumor height; predictors and outcomes;success rate;fluorescence angiography; indocyanine green angiography
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2014年第15期2874-2876,共3页 中华医学杂志(英文版)
关键词 circumscribed choroidalhemangiomas photodynamic therapy tumor height predictors and outcomes success rate fluorescence angiography indocyanine green angiography circumscribed choroidalhemangiomas photodynamic therapy tumor height predictors and outcomes success rate fluorescence angiography indocyanine green angiography
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