牙周治疗对中度和重度牙周炎伴高血脂患者血脂水平的影响

The effects of periodontal therapy on serum lipid level in patients with periodontitis and hyperlipidemia

目的:观察牙周治疗对牙周炎伴高血脂患者血脂水平的影响。方法:将61例慢性牙周炎伴高血脂患者随机分为对照治疗组(n=30)和干预治疗组(n=31)。对照治疗组患者予龈上洁治和抛光;干预治疗组患者予龈上洁治和抛光,一次法完成龈下刮治和根面平整,治疗后2周内予0.2%复方氯己定漱口。在基线点以及牙周治疗后2、6个月时对所有患者进行牙周检查和血脂检测。结果:治疗后2个月和6个月,干预治疗组的甘油三酯水平与对照治疗组相比明显降低(P<0.05),高密度脂蛋白水平与对照治疗组比较显著升高(P<0.05),总胆固醇和低密度脂蛋白水平与对照治疗组比较差异无统计学意义。结论:对牙周炎伴高血脂患者进行牙周干预治疗可获得血脂水平的改善。

Objective：To evaluate the effects of periodontal treatment with scaling and root planning supplemented with chlorhexidine on plasma lipids in patients with chronic periodontitis and hyperlipidemia（CPH）.Methods：6 1 patients with CPH were randomly assigned into control-treatment group（n=30）and intensive-treatment group（n=31）.Patients in the control-treatment group underwent a standard cycle of supragingival mechanical scaling and polishing.Patients in the intensive-treatment group underwent the adjunctive full-mouth intensive removal of subgingival dental plaque biofilms with the use of scaling and root planning.Periodontal parameters,total cholesterol（TC）,triglycerides（TRG）,high-density lipoprotein（HDL）and low-density lipoprotein（LDL）were measured before treatment and 2 and 6 months after treatment.Results：2 and 6 months after treatment,TRG was significantly lower in the intensive-treatment group than that in the control-treatment group（P〈0.05）,the levels of HDL were significantly higher（P〈0.05）;however, the levels of total cholesterol and LDL,in the intensivetreatment group were not significantly different from those in the control-treatment group 2 and 6 months after therapy.Conclusion：Intensive periodontal treatment may improve serum lipid levels in patients with hyperlipidemia and chronic periodontitis.