钛片阻断下颌骨单侧骨断面的牵张成骨的实验研究

Experimental study of mandibular distraction osteogenesis with titanium membrane as the transition disc

目的研究钛片阻断下颌骨单侧骨断面的牵张成骨。方法新西兰白兔10只,行单侧下颌骨截开,用钛膜覆盖一侧切开端整个骨面,延迟5 d,以每天0.8 mm、每天2次牵引8 mm,固定16周,分别行大体、放射学和组织学观察。结果 3只完成牵张,2只钛片与骨断端间有部分新骨形成。结论钛作为有可能的输送盘还需进一步研究。

Objective To investigate whether titanium material could be used as transition disc during distraction osteogenesis. Methods Unilateral mandible split was performed in 10 New Zealand white rabbits. Titanium membrane was inserted into the fracture site and covered one side surface. After 5 days＇ delay, distraction was performed 0.8 mm per day and twice a day. Total distraction length was 8 mm. After 16 weeks＇fixation,the new bones were grafted and subjected to histological radiologic and pathological analysis. Results Successful distractions were found in 3 of the rabbits. Some new bone formation could be detected in 2 of the rabbits. Conclusions Titanium material might be used as the transition disc during osteogenesis distraction.