慢性呼吸衰竭患者报告临床结局量表的信效度分析

Development of A Patient-reported Outcomes Scale for Chronic Respiratory Failure: A Psychometric Test

目的对自行编制的慢性呼吸衰竭患者报告临床结局(PRO)量表进行信度、效度和可行性的评价。方法采用慢性呼吸衰竭PRO量表对太原市8所医院461份样本(慢性呼吸衰竭患者364份,健康人97份)进行自评量表式调查,考评量表的信度、效度和可行性。结果慢性呼吸衰竭PRO初量表共包含51个条目,各领域的克朗巴赫系数如下:生理领域0.874,心理领域0.877,社会领域0.807,治疗领域0.712,总量表0.905,总体上该量表的克朗巴赫系数高。验证性因子分析结果显示该量表具有良好的结构效度。比较慢性呼吸衰竭患者与健康人在每个方面的测评结果,各方面分量表及总量表得分差异均有统计学意义。调查表的回收率、有效率均达95%以上,患者一般在15 min左右完成量表,表明该量表有较高的可行性。结论慢性呼吸衰竭PRO量表具有较好的信度、效度和可行性。

Objective To evaluate the reliability, validity and feasibility of a patient-reported outcomes （PRO） scale in the subjects with respiratory failure. Methods 364 patients with chronic respiratory failure and 97 healthy subjects were face-to-face interviewed by well-trained investigators, and the data of respiratory failure -PRO instrument were collected. The psychometric performance such as reliability, validity,responsiveness and clinical feasibility in the respiratory failure -PRO instrument was evaluated. Results The Cronbach＇s alpha coefficient of the respiratory failure -PRO instrument and each dimension were greater than 0.7. Factor analysis showed that the instrument had good construct validity. The scores of each of the facets and total scores between the patients and the healthy subjects were different. The recovery rate and the efficient rate of the questionnaire were more than 95%, and the time required to complete a questionnaire was within 15 minutes, indicating that the scale had a high clinical feasibility. Conclusion The respiratory failure -PRO instrument has good reliability, validity, responsiveness and clinical feasibility.