拜阿司匹灵联合依达拉奉治疗脑血栓形成的研究

Clinical research on Bayaspirin combined with Edaravone in treatment of cerebral thrombosis

目的探讨拜阿司匹灵联合依达拉奉治疗脑血栓形成患者的临床疗效。方法对162例脑血栓形成患者,分为对照组81例和治疗组81例。对照组:拜阿司匹灵0.1,1次/天,生理盐水100 ml静脉滴注,2次/天;一个疗程为14天。治疗组:拜阿司匹灵0.1,1次/天,依达拉奉30 mg/次,加入生理盐水100 ml稀释后静脉滴注,2次/天;一个疗程为14天。比较对照组和治疗组的临床疗效。结果对照组总有效率为85.18%,治疗组总有效率为95.06%;两组总有效率比较差异有统计学意义(P<0.05)。结论两组都能改善脑血栓形成患者的临床症状和体征,促进神经功能缺损恢复,治疗组临床效果更显著,未发现不良反应。

Objective To investigate the clinical efficacy of Bayaspirin combined with Edaravone in the treatment of cerebral thrombosis .Methods 162 cases of patients with cerebral thrombosis were divided into two groups：the control group （ n=81 ） and the treatment group （ n=81 ） .The patients in the control group took Bayaspirin 0.1 once a day and got intravenous drip of saline 100ml twice a day 14 days for a course.The patients in the treatment group took Bayaspirin 0.1 once a day and got intravenous drip of Edaravone 30mg diluted with saline 100ml twice a day 14 days for a course .Compare the efficacy in two groups .Results The total effective rate in the control group was 85.18%, and 95.06%in the treatment group.The difference in the two groups was statistically significant （P〈0.05）.Conclusions The two groups can both improve the clinical symptoms and signs of the patients with cerebral thrombosis , promote the recovery of neural function .However, the clinical effect in the treatment group is more significant and adverse reaction is not found .