容量法测定复方肝水解物片中重酒石酸胆碱的含量

Determination the Content of Cholini Bitatratis in Compound Hepar Extract Tablets by Volumetry

目的：建立复方肝水解物片的含量测定方法。方法：根据化学药品地方标准上升国家标准（第十三册）中重酒石酸胆碱含量测定方法,测定复方肝水解物片中重酒石酸胆碱的含量。结果：重酒石酸胆碱在0.30~0.50g范围内与消耗0.1mol/L的氢氧化钠滴定液体积呈线性关系（r=0.9999）,平均回收率为99.82%,RSD=0.19%（n=9）。结论：容量法简便、迅速、准确可作为复方肝水解物片的质量控制。

Objective： To determine of content the compound hepar extract tablets by Volumetry. Method： According to the standard of choline bitatratis in the Vol. 13 of chemicals local standard upgrade to national standard, to determine the content of choline bitatratis in compound hepar extract tablets. Result： The choline bitatratis and the consumption of 0. 1 mol/L NaOH was linear relation- ship with in a range of 0. 30 - 0. 50g （r = 0. 9999）, the average recovery was 99. 82%, RSD = 0. 19% （ n = 9） . Conclusion： The method is simple, repid and sensitive, it can be used for the quality control of compound hepar extract tablets.