虹膜定位波前像差引导的LASIK与传统LASIK治疗高度近视像差的变化与对比敏感度、眩光敏感度关系

The Relationship of Changes of Aberrations and Contrast Sensitivity and Glare sensitivity Between Iris Location Wavefront - guided LASIK and Traditional LASIK in Treatment of High Myopia

目的：比较虹膜定位波前像差引导的准分子激光原位角膜磨镶术（LASIK）和传统LASIK矫正高度近视术后3个月时波前像差的变化与对比敏感度、眩光敏感度的关系，探讨像差对视觉质量的影响。方法：将行虹膜定位波前像差引导的LASIK的高度近视患者9例（17眼）作为试验组，行传统LASIK的近视患者8例（14眼）作为对照组。对试验组和对照组术后3个月的视力、波前像差、对比敏感度和眩光敏感度进行统计学分析。结果：（1）试验组、对照组术后3个月的视力无统计学意义（P〉0．05），波前像差Zernike函数c4（离焦）、C7（垂直彗差）、C8（水平彗差）、三叶草差（C6、C9）、C12（球差）、RMSg（总体像差均方根值）、RMSh（高阶像差均方根值）无统计学意义（P〉0．05）。（2）术后3个月比较对比敏感度，白天在低频区3．0c／d、中频区6．0c／d空间频率下，有统计学意义（P〈0．05）；晚上在低频区3．0c／d空间频率下，有统计学意义（P〈0．05）。白天＋眩光在低频区3．0c／d空间频率下，有统计学意义（P〈0．05）。结论：虹膜定位波前像差引导的LASIK较传统LASIK矫正高度近视无更好的视觉质量。

Objective： By comparing the relationship of changes of aberrations and contrast sensitivity and glare sensitivity between iris location wavefront - guided laser in situ keratomileusis （LASIK） and traditional LASIK in treatment of high myopia at 3 months postopera- tively, to investigate the effect of aberrations on visual quality. Methods： 9 patients （17 eyes） for high myopia were selected as trial group ,which performed iris location wavefront - guided LASIK and 8 patients （ 14 eyes） for high myopia were selected as the control group ,which performed traditional LASIK. Analyse visual acuity, wavefront aberrations, contrast sensitivity and glare sensitivity at 3 months postoperatively for trial group and control group. Results ： （ 1 ） At 3 months postoperatively for trial group and control group , visu- al acuity was not significant （ P 〉 0.05 ） , in zernike function of wavefront aberrations, CA （defocus） , C7 （ vertical coma）, C8 （ horizontal coma）, trefoil aberration（ C6, C9 ） , C12 （ spherical aberration）, RMSg （ root of mean square of general aberration）, RMSh （ root of mean square of higher aberration） were not significant （P 〉 0.05 ）. （2）At 3 months postoperatively by comparing contrast sensitivity, During the day the low frequency 3.0c/d and the middle frequency area 6.0e/d were significant （ P 〈 0.05 ）. At night the low frequency 3.0c/d was significant （ P 〈 0.05 ）. During day ＋ glare the low frequency 3.0e/d was significant （ P 〈 0.05 ）. Conclusion： Iris Location wavefront - guided LASIK has not better visual quality than traditional LASIK for treatment of high myopia.