联合治疗慢性阻塞性肺疾病急性加重期合并肺性脑病135例临床疗效评价

The clinical curative effect evaluation of 135 patients of chronic lung disease of acute aggravating period with pulmonary encephalopathy

目的对联合治疗慢性阻塞性肺疾病急性加重期(AECOPD)合并肺性脑病的临床疗效进行探讨。方法选择2010年1月至2012年12月本院收治的135例AECOPD合并肺性脑病患者,常规治疗基础上进行无创正压通气(NIPPV),探讨其通气前和通气后2小时和24小时治疗效果。结果常规治疗联合NIPPV治疗AECOPD合并肺性脑病患者前后的相应指标有所变化,135例患者通气后2小时和24小时心率(HR)和呼吸频率(RR)均较通气前下降,差异具有显著性;通气后2小时和24小时pH、PaO2和SaO2均较通气前上升,PaCO2均较通气前下降,比较差异具有显著性。结论常规治疗联合NIPPV治疗AECOPD合并肺性脑病疗效较好,值得在临床中进一步推广使用。

Objective To explore the clinical curative effect evaluation of 135 patients of chronic lung disease of acute aggravating period with pulmonary encephalopathy. Method Chosed 135 cases of chronic lung disease of acute aggravating period with pulmonary encephalopathy in our hospital from January 2010 to December 2012, besides the conventional treatment, we joined the NIPPV methods, so we can explore its ventilation before 2 hours and 24 hours after treatment. Result Conventional treatment combined with NIPPV bring some changes. After the treatment of 2 hours and 24 hours the HR, RR and PaCO2 were lower than the indicators of before the treatment and the pH, PaO2, SaO2 were higher. Conclusion The clinical curative effect evaluation of chronic lung disease of acute aggravating period with pulmonary encephalopathy was well. It is worthy of further popularization in clinical use.