甲状腺Langerhans细胞组织细胞增生症的超声声像图表现

Ultrasound imaging of Langerhans cell histiocytosis involving thyroid

目的探讨甲状腺Langerhans细胞组织细胞增生症(LCH)的超声声像图表现。方法回顾性分析5例甲状腺LCH患者甲状腺超声声像图表现,其中4例患者经病理学诊断,1例为临床诊断。结果甲状腺LCH超声声像图表现为:(1)甲状腺明显增大,弥漫回声减低,不均匀,边界清或不清,彩色多普勒血流成像(CDFI):内见丰富血流信号;(2)甲状腺内见大小不等的结节样、片状和条状低回声,与正常甲状腺组织边界清,CDFI:内未见血流信号。结论甲状腺LCH超声声像图无特异性,主要表现为明显增大、弥漫回声减低且不均匀。超声引导下细针抽吸细胞学检查对诊断甲状腺LCH有帮助,但诊断率低。

Objective To investigate the ultrasound imaging of Langerhans cell histiocytosis involving thyroid. Methods Ultrasound imaging findings of five Langerhans cell histiocytosis involving thyroid were analyzed retrospectively, 4 were diagnosed by pathology, and 1 was diagnosed through clinical manifestations. Results Two types of ultrasound imaging were observed in Langerhans cell histiocytosis of thyroid：（1） The thyroid was significantly enlarged, presented diffuse and heterogenous hypoechogenicity with clear or unclear border. Color Doppler flow imaging（CDFI） showed abundant flow imaging.（2） Hypoechoic nodules, flakes and strips in varying sizes were distributed in the thyroid with clear boundary between the foci and normal gland tissue. No blood flow signal was found within hypoechogenicity. Conclusions There is no specific ultrasonographic features of Langerhans cell histiocytosis involving thyroid. The general sonographic finding is the significantly enlarged thyroid, with diffuse and heterogenous hypoechogenicity. Fine needle aspiration is useful for the diagnosis, however, the diagnostic rate is low.