高危因素早期干预对妊娠期糖尿病妊娠结局的影响

The Effect of Early Intervention of High Risk Factors on Pregnancy Outcomes in Gestational Diabetes Mellitus

目的早期干预具有妊娠期糖尿病(GDM)高危因素的孕产妇,观察其妊娠结局。方法对2010年5月至2013年3月我院产科建档的具有妊娠期糖尿病高危因素的孕妇随机分为研究组(726例)和对照组(708例),采用前瞻性随机对照研究方法,针对妊娠期糖尿病高危因素进行早期干预,观察两组妊娠结局。结果对照组的剖宫产、妊娠期高血压疾病、产后出血、羊水过多、巨大儿的发生率高于研究组(P<0.05);而胎膜早破、羊水过少、GDM、早产、低出生体质量儿、胎儿畸形、胎儿窘迫及新生儿窒息的发生率两组无统计学差异(P>0.05)。结论妊娠期糖尿病严重危害母亲及胎儿的健康,对具有妊娠期糖尿病高危因素的孕妇进行早期干预,可有效减少妊娠期糖尿病引起的母婴并发症的发生。

Objeetive Early intervention with gestational diabetes mellitus（GDM）risk factors for maternal, observes its pregnancy outcome. Methods The pregnant women with high risk factors of gestational diabetes mellitus documented in our hospital obstetric from May 2010 to March 2013 were randomly divided into study group（726）and control group（708）. Prospective randomized comparison study methods are used, perform early intervention against the gestational diabetes-risk factors, and observe two groups of pregnancy outcomes. Results The incidence rate of Cesarean section, hypertensive disorders in pregnancy, postpartum bleeding, polyhydramnios of the control group is higher than that of macrosomia research group（P〈0.05）; there is no statistical significant differences for the incidence rate of premature rupture of membranes, oligohydramnios, GDM, preterm birth, low bkrth weight, fetal malformations, neonatal asphyxia and fetal distress of the two groups（P〉0.05）.Conelnsion Diabetes seriously endangers the health of the mother and fetus during pregnancy. With early intervention of high risk factors of gestational diabetes meUitus pregnant women, We incidence of maternal and neonatal complications of gestational diabetes can be effectively reduced.