依那普利联合马尼地平治疗原发性高血压的效果

The Effect of Manidipine Enalapril Treatment of Essential Hypertension

目的重点研究和探讨依那普利联合马尼地平治疗原发性高血压的临床疗效。方法利用回顾性分析的方法研究和比较对我院于2010年1月1日至2012年12月31日期间收治的140例原发性高血压患者的临床资料进行回顾性对照分析。将患者随机分为2组,对照组总计70例应用依那普利单药进行治疗;观察组总计70例应用依那普利与马尼地平进行联合治疗。然后将2组数据结果进行分析,分析探讨两组患者疗效的结果。结果观察组总有效率为91.43%,对照组总有效率为75.71%,观察组患者的治疗效果显著好于对照组(P<0.05)。结论依那普利联合马尼地平治疗原发性高血压患者具有很好的临床疗效目前已经成为治疗原发性高血压患者的主要方法,对我国治疗原发性高血压的发展具有重要价值,值得临床借鉴和进一步推广。

Objective Focus on research and study Manidipine Enalapril treatment of essential hypertension clinical efficacy. Methods Retrospective analysis methods and comparative studies in our hospital in January 1, 2010-2012 on December 31 treated 140 patients with essential hypertension clinical data were retrospectively analyzed. The patients were randomly divided into two groups, control group total 70 cases of enalapril monotherapy for treatment; observation group total 70 eases of enalapril combination therapy with Manidipine. Then the two sets of data to analyze the results, analyze the results of the efficacy study two groups of patients. Results The total effective rate was 91.43% in the control group, the total effective rate was 75.71%, the therapeutic effect of the observation group were significantly better than the control group（P 〈0.05）. Conclusion Manidipine enalapril treatment of essential hypertension in patients with good clinical efficacy has become the treatment of essential hypertension in patients with primary method of treatment of hypertension for the development of significant value, is worthy of reference and further promotion.