探讨急性脑梗死患者血浆纤维蛋白原与D-二聚体水平的变化及其临床意义

Explore the Changes and Clinical Significance of Plasma Fibrinogen and Acute D-dimer Levels in Patients with Cerebral Infarction

目的对急性脑梗死患者血浆纤维蛋白原与D-二聚体水平变化的临床变化以及价值进行分析和探讨。方法以我院在2012年1月至2013年5月收治的100例急性脑梗死患者为研究对象,将其设为实验组,并同期抽取40例健康者为对照组,采用Clauss法以及乳胶免疫比浊法对两组对象的血浆纤维蛋白原以及D-二聚体水平进行检测。结果实验组患者的血浆纤维蛋白原以及D-二聚体水平明显高于对照组,差异存在统计学意义,P<0.05;病情越为严重,则血浆纤维蛋白原以及D-二聚体水平越高,差异存在统计学意义,P<0.05。结论血浆纤维蛋白原以及D-二聚体水平变化对急性脑梗死患者的临床诊断具有显著的价值和作用。

Objective To explore and analyze plasma fibronectin in patients with acute cerebral infarction of fibrinogen and D-direct levels in two clinical changes and value. Methods In our hospital in 100 cases of acute cerebral infarction from 2012 January to 2013 May in our hospital as the research object, set it as the experimental group, and 40 healthy subjects were selected as control group, using Clauss method and immunoturbidimetry method on two groups of plasma fibrinogen and D-dimer level two detection. Results The experimental group of plasma fibrinogen and D-dimer level was two higher than that of the control group, the difference had statistical significance, P〈0.05; the illness is more serious, then the plasma fibrinogen and D- dimer levels two higher, there were significant differences, P〈0.05. Conclusion The value and significant role in clinical diagnosis of plasma fibrinogen and D-dimer levels of two patients with acute cerebral infarction.