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阿托伐他汀对慢性肾小球肾炎患者的临床疗效研究 被引量:1

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摘要 目的研究阿托伐他汀对慢性肾小球肾炎的肾脏保护作用。方法随机将98例慢性肾小球肾炎患者随机分为2组,对照组常规治疗组、观察组阿托伐他汀组治疗,疗程6个月,观察3个月、6个月的血脂、肾功能、尿蛋白情况。结果治疗3个月后阿托伐他汀组在尿蛋白(U-pro)、肌酐(Scr)、内生肌酐清除率(Ccr)、尿素氮(BUN)均优于对照组(P<0.01),而血脂在治疗3个月后无显著差异。治疗6个月后阿托伐他汀组在蛋白尿、肾功能及血脂上明显优于常规治疗组。结论阿托伐他汀具有较好的肾脏保护作用,并且具有降脂外的肾保护作用。
出处 《中国医药指南》 2014年第24期179-180,共2页 Guide of China Medicine
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