无溶剂条件下氧化锌催化合成肉桂腈

Synthesis of cinnamonitrile catalyzed by zinc oxide under solvent-free conditions

以ZnO为催化剂,在无溶剂条件下,肉桂醛和盐酸羟胺通过一步法合成了肉桂腈。ZnO催化合成肉桂腈的适宜反应条件为:n(肉桂醛)∶n(盐酸羟胺)=1∶1.5,催化剂用量为肉桂醛质量的6%,反应温度120℃,反应时间1 h,肉桂腈的收率可达90.2%。ZnO商业上容易得到,是一种环境友好催化剂。

Cinnamonitrile was synthesized directly from cinnamaldehyde and hydroxylamine hydrochloride in the presence of ZnO as the catalyst under solvent-free conditions. The results showed that the yield of cinnamonitrile is up to 90 . 2% when the molar ratio of cinnamaldehyde to hydroxylamine hydrochloride is 1：1 . 5 ,the amount of catalyst is 6%（ based on the mass of cinnamaldehyde ）,reaction temperature is 120 ℃ and the reaction time is 1 h. ZnO is a readily available and environment-friendly catalyst.