硫醚氧化成砜的新方法

A Novel Synthetic Method for Oxidation of Sulfide to Sulfone

以丙酮为溶剂,30%双氧水为氧化剂,钨酸钠为催化剂,研究了硫醚(烃基硫醚、苄基硫醚、不饱和硫醚、含二级胺的饱和硫醚、含三级胺的饱和硫醚)被氧化成相应砜的反应。结果表明,饱和烃基硫醚能方便的氧化为相应的砜类;苄基硫醚、含三级胺官能团的饱和硫醚也能氧化成相应的砜;含苄基和氨基的硫醚不能氧化成相应的砜。化合物的结构经1H NMR和13C NMR确证。

In this paper, direct oxidation of a series of sulfides to sulfones by 30% hydrogen peroxide using sodium tungstate as the catalyst and actone as the solvent is reported. It was found that saturated hydrocarbon sulfides can be oxidized to the sulfones conveniently under this condition, benzyl sulfides and containing tertiary amine functional group saturated sulfides can be oxidized to the sulfones under this condition without affecting the benzyl and amine. The structures were confirmed by ^1H NMR and ^13C NMR.