脑卒中后抑郁的相关因素研究

Analysis on related factors of post-stroke depression

目的分析中老年脑卒中后抑郁(PSD)的患病情况及相关危险因素。方法对2011年3月至2012年3月初发的68例脑卒中患者进行6个月随访研究。采用汉密尔顿抑郁量表(HAMD17)、日常生活能力量表(ADL)、艾森格个性问卷(EPQ)、临床神经功能缺损程度评分(NDS)、家庭关怀度量表(APGAR)评估患者,调查PSD患病率并对其相关因素进行Logistic回归分析。结果 PSD发生率为36.76%(25/68);Logistic回归分析显示PSD与年龄、是否合并基础疾病、个性、日常生活能力、神经功能缺损程度等因素无明确关系,而与脑卒中部位、性别、经济情况、家庭关怀度等因素关系密切。结论 PSD患病率较高,女性、左侧脑卒中、经济状况差、家庭关怀度差是其主要危险因素。

Objective To investigate the morbidity rate and risk factors of post-stroke depression in middle-aged and elderly per-sons with the stroke .Methods From March 2011 to March 2012 ,68 cases of stroke patients were followed up for 6 months after the first stroke .Hamilton Depression Scale-17 ,Activity of Daily Living Scale ,Eysenck Personality Questionnaire ,Scores of Neuro-logical Deficit and Family APGAR Index were used to investigate the morbidity rate and risk factors of PSD in 6 months after the attack of stroke .Results The morbidity rate of PSD was 36 .76% （25/68） in 6 months after the first stroke .Logistic regression a-nalysis indicated that the morbidity rate of PSD was without a clear relationship with age ,whether or not combined with basic disea-ses ,personality ,daily life ability and neurologic impairment .It was closely related with stroke position ,gender ,economy and family care .Conclusion The morbidity rate of PSD is considerable and the major risk factors of PSD are female ,left brain stroke ,poor e-conomic condition and lack of family care .