发热伴血小板减少综合征的血象及骨髓象分析

Hemogram and myelogram analysis on the severe fever with thrombocytopenia syndrome

目的研究发热伴血小板减少综合征(SFTS)患者的血象和骨髓象特点。方法回顾性总结分析30例SFTS确诊患者的资料。结果 SFTS布尼亚病毒(SFTSV)感染机体可导致外周血白细胞、血小板减少,网织红细胞减低,并出现异型淋巴细胞,在疾病极期-晚期骨髓增生减低,造血细胞明显受抑,并出现较多噬血细胞。结论外周血和骨髓检测对SFTS的诊断、预后判断有一定的临床意义。

Objective To investigate the features of hemogram and myelogram from patients with severe fever with thrombocytopenia syndrome（ SFTS）. Methods The data of 30 patients confirmed as SFTS were analyzed retrospectively. Results SFTS bunyavirus（ SFTSV） infection mechanism was prone to develop leukopenia,thrombopenia,reticulocyte decreasing and atypical lymphocyte in peripheral blood. In the progression and the late stages,the patients usually had a hypocellular bone marrow with hematopoietic cell decreasing and macrophage ingestion blood cell increasing. Conclusions Hemogram and myelogram analysis is very important for the diagnosis and prognosis of SFTS.