期刊文献+

肠道菌群与肠易激综合征关系的研究进展 被引量:10

下载PDF
导出
摘要 人体内存在数量庞大的肠道菌群,在肠易激综合征(IBS)等多种疾病的发病机制中起着重要的作用。近年来,以宏基因组学为代表的培养非依赖性技术方法为全面准确地分析肠道菌群提供了有力的工具。肠道菌群在IBS发病中的作用已逐渐被阐明,益生菌干预成为调节肠道菌群的重要手段。此文对上述研究进展作一综述。
出处 《国际消化病杂志》 CAS 2014年第4期230-233,共4页 International Journal of Digestive Diseases
  • 相关文献

参考文献1

二级参考文献49

  • 1Talley NJ, Spiller R. Irritable bowel syndrome: a little understood organic bowel disease? Lancet 2002; 360:555-564.
  • 2Balsari A, Ceccarelli A, Dubini F, Fesce E, Poli G. The fecal microbial population in the irritable bowel syndrome. Microbiologica 1982; 5:185-194.
  • 3Posserud I, Stotzer PO, Bjornsson ES, Abrahamsson H, Simren M. Small intestinal bacterial overgrowth in patients with irritable bowel syndrome. Gut 2007; 56:802-808.
  • 4Malinen E, Rinttila T, Kajander K, Matto J, Kassinen A,Krogius L, Saarela M, Korpela R, Palva A. Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR. Am J Gastroenterol.2005; 100:373-382.
  • 5Kassinen A, Krogius-Kurikka L, Makivuokko H, Rinttila T, Paulin L, Corander J, Malinen E, Apajalahti J, Palva A. The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects. Gastroenterology 2007; 133:24-33.
  • 6King TS, Elia M, Hunter JO. Abnormal colonic fermentation in irritable bowel syndrome. Lancet 1998; 352:1187-1189.
  • 7Zoetendal EG, von Wright A, Vilpponen-Salmela T, Ben-Amor K, Akkermans AD, de Vos WM. Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces. Appl Environ Microbiol 2002; 68: 3401-3407.
  • 8Lepage P, Seksik P, Sutren M, de la Cochetiere MF, Jian R, Marteau P, Dore J. Biodiversity of the mucosa-associated microbiota is stable along the distal digestive tract in healthy individuals and patients with IBD. Inflamm Bowel Dis 2005; 11:473-480.
  • 9Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA. Functional bowel disorders and functional abdominal pain. Gut 1999; 45 Suppl 2: II43- II47.
  • 10Leon-Barua R, Gilman RH, Rodriguez C, Bonilla JJ, Yi A, Maurtua D, Sack RB. Comparison of three methods to obtain upper small bowel contents for culture. Am J Gastroenterol 1993; 88:925-928.

共引文献32

同被引文献98

引证文献10

二级引证文献84

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部