新疆紫草油和滇紫草油治疗烧烫伤的药效学比较

Pharmacodynamic Study on the Comparison of Xinjiang Borage Oil and Yunnan Lithospermi Oil for the Treatment of Burn and Scald

目的观察新疆紫草油和滇紫草油对实验性浅Ⅱ度烧、烫伤大鼠的治疗作用,比较二者的差异,为紫草油原料药材的选择提供理论依据。方法建立实验性大鼠浅Ⅱ度烧、烫伤模型,观察新疆紫草油和滇紫草油对创面愈合面积和创面愈合时间的影响。结果新疆紫草油和滇紫草油均能促进创面愈合,缩短创面愈合时间。结论新疆紫草油和滇紫草油均有明显治疗烧、烫伤的作用,新疆紫草和滇紫草均可作为紫草油的原料药材。

OBJECTIVE To observe Xinjiang borage oil and Yunnan lithospermi oil＇s effect on experimental shallow Ⅱ degree burn and scald rats, and comparing the difference to provide theoretical basis for the choice of Arnebiae Radix oil raw material medicine. METHODS Establishing the experimental shallow Ⅱ degree burn and scald in rats models, then observed the Xinjiang borage oil and Yunnan lithospermi oil＇s effect on recovering time and area of wounds. RESULTS Xinjiang borage oil and Yunnan lithospermi oil both had positive effects on recovering time and area of wounds. CONCLUSION Xinjiang borage oil and Yunnan lithospermi oil both have obvious curing effects on burn and scald, can be used as raw material medicine of Arnebiae Radix oil.