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埃索美拉唑联合莫沙必利治疗胃食管反流病的临床疗效观察 被引量:8

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摘要 目的观察埃索美拉唑联合莫沙必利治疗胃食管反流病的临床疗效,为临床治疗提供参考依据。方法将100例胃食管反流病患者随机分为观察组和对照组各50例,观察组采用埃索美拉唑联合莫沙必利治疗,对照组采用奥美拉唑联合莫沙必利治疗。治疗4周时及8周时分别比较2组临床疗效。治疗8周时胃镜下比较胃黏膜恢复情况。结果第4周治疗结束后观察组的总有效率为88%明显高于对照组的68%,第8周治疗结束后观察组的总有效率为96%明显高于对照组的78%,治疗8周后,在食管黏膜的愈合情况方面,观察组总有效率为98%明显高于对照组的76%,差异均有统计学意义(P<0.05)。结论埃索美拉唑联合莫沙必利治疗胃食管反流病的临床效果较好,疗效优于奥美拉唑联合莫沙必利的治疗。
作者 王自启
出处 《临床合理用药杂志》 2014年第25期34-35,共2页 Chinese Journal of Clinical Rational Drug Use
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  • 1陆星华,张泰昌.反流性食管炎诊断及治疗指南(2003年)[J].中华消化内镜杂志,2004,21(4):221-222. 被引量:842
  • 2王任之,邓兴臣,陈村龙,黄飞雄,吴淑媛.倍剂泮托拉唑联合多潘立酮治疗胃食管反流病的临床研究[J].现代消化及介入诊疗,2006,11(1):35-36. 被引量:7
  • 3Vleggaar FP, Siersema PD. Barrett' s esophagus, reflux esophagitis,and cosinophilic esophagitis [ J ]. Gastrointest Endose, 2012,76 (5) :496 -500.
  • 4Nagahara A, Hojo M, Asaoka D, et al. Clinical fealurc of asymptomatic reflux esophagitis in patients who underwent upper gastrointestinal endoscopy [ J ]. J Gastroenterol Hepatol,2012,27 ( 3 ) : 53 - 57.
  • 5Grande M, Sileri P, Attina GM, et al. Nonerosive gastroesophageal reflux disease and mild degree of esophagitis: comparison of symptoms endoscopic, manometric and pH-metrie patterns[J]. Worht J Surg Oncol,2012,10(3):84.
  • 6Molioa-lnfante J,Zamorano J. Distinguishing eosinophilic esophagitis from gastroesophageal reflux disease upon PPI refractoriness: what about PPI - responsive esophageal eosinophilia? [ J ]. Digestion,2012,85 (5) :210.
  • 7Weijenborg PW, Cremonini F,Smout A J, et al. PPI therapy is equally effective in well-defined non-erosive reflux disease and in reflux esophagitis: a meta-analysis [ J ]. Neurogastroenterol Motil, 2012,24(8) :747 -757.
  • 8Tolia V, Gilger MA, Barker PN,et al. Healing of erosive esophagitis and improvement of symptoms of gastroesophageal reflux disease after esomeprazole treatment in children 12 to 36 months oht [ J ]. J Pediatr Gastroenterol Nutr,2010,51 ( 5 ) :593 - 598.
  • 9Guimaraes EV ,Guerra PV, Penna FJ. Management of gastroesophageal reflux disease and erosive esophagitis in pediatric patients: f()- cus on delayed-release esomeprazole [ J ]. Ther Clin Risk Manag, 2010,6(8):531 -537.
  • 10Miwa H, lnoue K, Ashida K, et al. Randomised clinical trial : efficacy of the addition of a prokinetic ,mosapride citrate, to omeprazole in the treatment of palicnts with non-erosive reflux disease-a double-blind, placebo-controlled study [J]. Aliment Pharmacol Ther, 2011, 33 (3) :323-332.

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