胺碘酮在冠心病快速型心律失常急诊治疗中的应用效果观察

Clinical effect of amiodarone in the treatment of coronary heart disease in emergency tachyarrhythmia

目的：分析胺碘酮在冠心病快速型心律失常急诊治疗中的临床效果。方法选取156例冠心病快速心律失常患者为研究对象，以随机数字表法分为治疗组与对照组各78例，治疗组规律性应用胺碘酮，对照组采取常规治疗，比较两组临床疗效。结果治疗组总有效率为88．4％，不良反应发生率为3．8％；对照组总有效率为71．8％，不良反应发生率14．1％。两组差异均有统计学意义（χ2＝18．33、13．91，均P＜0．05）。治疗组房颤共36例，转复34例，转复率94．4％，其次为室性期前收缩（90．6％）。结论冠心病快速心律失常急诊应用胺碘酮安全有效，不良反应少，对于房颤及室性期前收缩效果最理想，值得临床推广使用。

Objective To investigate the effect of amiodarone in the treatment of coronary heart disease in emergency tachyarrhythmia .Methods 156 cases of coronary heart disease in patients with tachyarrhythmias were randomly divided into the treatment group and control group ,78 cases in each group .The treatment group was given amiodarone,the control group was given conventional therapy .The clinical effect was compared between the two groups.Results The total effective rate,incidence rate of side effects in treatment group were 88.4%,3.8%,those in the control group were 71.8%,14.1%.The differences between the two groups were significant （χ2 =18.33, 13.91,P〈0.05）.In the treatment group,36 cases had atrial fibrillation,cardioversion 34 patients,the cardioversion rate was 94.4%,followed by premature ventricular contractions （90.6%）.Conclusion Amiodarone in the treatment of coronary artery disease emergency tachyarrhythmia is safe and effective ,has fewer adverse reactions ,the best results for atrial fibrillation and ventricular premature beats ,it is worthy of clinical use .