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顽固性高血压的器械治疗：抑制交感神经活性

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摘要 世界范围内约34％的成人患有高血压[1]，高血压已成为主要致死原因，占死亡原因的13％[2]。高血压的治疗主要包括生活方式的改善和药物治疗。然而，许多患者在接受治疗后血压仍未得到良好的控制。
作者 钱菊英 秦晴
机构地区 复旦大学附属中山医院、上海市心血管病研究所
出处 《上海医学》 CAS CSCD 北大核心 2014年第7期554-558,共5页 Shanghai Medical Journal
关键词 顽固性高血压 器械治疗 交感神经活性 世界范围 致死原因 死亡原因 药物治疗 生活方式
分类号 R544.1 [医药卫生—心血管疾病]
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参考文献30

  • 1VERLOOP W L, VOSKUIL M, DOEVENDANS P A. Renal denervation: a new treatment option in resistant arterial hypertension[J]. Neth Heart J, 2013, 21(2): 95-98.
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二级参考文献13

  • 1Calhoun DA, Jones D, Textor S, et al. Resistant hypertension:diagnosis, evaluation and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension, 2008, 51 : 1403-1419.
  • 2Krum H, Sobotka P, Mahfoud F, et al. Device-based antihypertensive therapy: therapeutic modulation of the autonomic nervous system. Circulation, 2011,123 : 209-221.
  • 3Krum H, Schlaich M, Whitbourn R, et al. Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof -of -principle cohort study. Lancet, 2009,373 : 1275-1281.
  • 4Schlaich MP, Sobotka PA, Krum H, et al. Renal sympathetic-nerve ablation for uncontrolled hypertension. N Engl J Med, 2009, 361 : 932-934.
  • 5Symplicity HTN-1 investigators. Catheter-based renal sympathetic denervation for resistant hyptersion: durability of blood pressure reduction out to 24 months. Hypertension, 2011,57:911-917.
  • 6Esler MD, Krum H, Sobotka PA, et al. Renal sympathetic denervation in patients with treatment-resistant hypertension ( The Symplicity HTN-2 Trial) : a randomised controlled trial. Lancet, 2010,376 : 1903-1909.
  • 7Prochnau D, Lauten A, Busch M, et al. Catheter-based radiofrequency ablation therapy of the renal sympathetic-nerve system for drug resistant hypertension in a patient with end-stage renal disease. Int J Cardiol,2012,154 : e29-30.
  • 8Ukena C, Mahfoud F, Kindermann I, et al. Cardiorespiratory response to exercise after renal sympathetic denervation in patients with resistant hypertension. J Am Coll Cardiol, 2011,58: 1176- 1182.
  • 9Levey AS, Bosch JP, Lewis JB, et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med, 1999, 130: 461-470.
  • 10Schlaich MP, Lambert E, Kaye DM, et al. Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and angiotensin neuromodulation. Hypertension, 2004, 43 : 169-175.

共引文献15

上海医学
2014年 第7期

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