摘要
目的：探讨光学相干层析术（ Optical Coherence Tomography ，OCT）在甲状腺手术当中应用的可行性。方法收集天津医科大学肿瘤医院行全甲状腺切除术患者的手术标本，包括甲状旁腺、淋巴结、脂肪组织及甲状腺组织，采集其OCT图像与常规检查结果进行比较。结果患者的甲状旁腺、淋巴结、脂肪组织、甲状腺组织均获得清晰的高分辨率OCT图像，不同组织间及淋巴结转移灶和正常结构间可明确区分，从样品准备到成像结束，OCT平均用时约1 min，冰冻检查为25 min。结论 OCT成像清晰可辨，与常规组织学图像相契合，不同组织间易于区分，且用时短，对组织无损伤，将OCT技术应用于甲状腺手术当中进行甲状旁腺的识别与淋巴结转移的判定具有一定的可行性。
Objective To investigate the feasibility of using optical coherence tomography （OCT）in thy-roid surgery .Methods Surgical specimen including parathyroid gland , lymph nodes , adipose tissue and thyroid tissue from patients receiving thyroid surgery in Tianjin Medical University Cancer Institute and Hospital were col -lected.OCT images were collected and the results were compared with the routine examination .Results Para-thyroid glands , lymph nodes , adipose tissue , and thyroid tissue can be obtained high-resolution OCT images .Dif-ferent tissues and metastatic lymph node can be clearly distinguished .OCT imaging took about 1 minute and fro-zen examination cost about 25 minutes.Conclusions OCT is a time-saving, non-invasive and cross-sectional imaging technique .It can obtain clear structural images of the internal microstructure of bio-tissues.OCT technol-ogy used in thyroid surgery including parathyroid identification and determination of lymph node metastasis is fea -sible.
出处
《中华内分泌外科杂志》
CAS
2014年第4期306-308,共3页
Chinese Journal of Endocrine Surgery
基金
国家自然科学基金资助项目，天津市应用基础与前沿技术研究计划重点项目
