环境因素对川芎饮片易挥发成分藁本内酯的影响

Effects of Environmental Factors on Volatile Constituent Ligustilide of Slices of Chuanxiong Rhizoma

目的:考察环境因素对川芎饮片易挥发性成分藁本内酯的影响。方法:采用正交试验设计,选取光照、氧气、温度、贮藏时间4个因素,每个因素选择3个水平,优选川芎饮片贮藏的最佳贮存条件。以藁本内酯为检测指标,采用高效液相色谱法测定川芎饮片中藁本内酯的含量。结果:温度是影响川芎饮片藁本内酯的首要因素,其次是时间,然后是光照,氧气的影响最小。结论:川芎饮片贮藏的最佳条件为密封包装,弱光低温下贮藏,贮藏时间越短越好。

Objective ： To investigate the effects of environmental factors on the volatile constituent ligustilide of the slices of Chua- nxiong Rhizoma. Methods：To study the optimal condition for storage of Chuanxiong Rhizoma slices by orthogonal design＋ The storage condition was optimized with illumination, oxygen, temperature and storage time as the observation factors. Each factor set three lev- els. With ligustilide as detection index, the content was measured by HPLC. Results：Temperature was the primary factor of the content of ligustilide,the second was the storage time, then the illumination. The influence of oxygen was the smallest. Conclusion：The optimum condition for storage of the slices of Chuanxiong Rhizoma is sealed package, under weak light and low temperature, with storage time as short as possible.