慢性阻塞性肺疾病加重期发生院内感染的相关因素分析

To analyze the related factors of nosocomial infection in AECOPD

目的 探讨慢性阻塞性肺疾病加重期（AECOPD）发生院内感染的相关因素.方法 回顾性的分析了2009年1月-2013年10月AECOPD院内继发感染的患者92例,并随机抽取相同时期无感染的AECOPD患者84例作为对照组,对其发生继发感染的细菌和病毒作出相应的鉴别诊断.结果 AECOPD调查组的患者中有42例（45.65％）是由鼻病毒、呼吸道合胞病毒、流感病毒感染所致,有61例（66.30％）是由流感嗜血杆菌、卡他莫拉菌、肺炎链球菌、铜绿单胞、金黄色葡萄球菌、副流感嗜血杆菌等感染所致,其检测结果和对照组相比差异显著,具有统计学意义（P＜0.05）.结论 AECOPD发生院内感染的主要因素有细菌学和病毒学因素,明确这些继发感染的相关因素对于患者后期的治疗能提供有力的理论依据.

Objective To investigate the exacerbation of chronic obstructive pulmonary disease （AECOPD） risk factors for nosocomial infection.Methods A retrospective analysis of 92 cases from 2009 January to 2013 October secondary infection among patients with AECOPD in hospital,and randomly selected the same period without infection in patients with AECOPD and 84 cases as control group.The incidence of secondary infections of bacteria and viruses to make differential diagnosis corresponding.Results 42 patients （45.65%） of AECOPD study group were caused by rhinovirus,respiratory syncytial virus or influenza virus infection,61 patients （66.30%） were caused by haemophilus influenzae,streptococcus pneumoniae,catarrh Mora bacteria,pseudomonas cell,staphylococcus aureus or haemophilus parainfluenzae infection.There was statistical significance of study group results compared with the control group （P 〈 0.05）.Conclusions The main factors of nosocomial infection with bacteriology and virology for AECOPD,and which provided a strong theoretical basis for the treatment of patients with late stage.