妊娠期孕妇外周血微量元素检测及其临床意义

Analysis of trace elements in peripheral blood of pregnant women and its clinical significance

目的了解孕妇外周血微量元素的水平和变化趋势,为孕期保健提供可靠的依据。方法使用BH5100原子吸收光谱仪对本院收治的250例围产期保健的早孕期、中孕期和晚孕期的3组孕妇和100例正常对照进行全血钙、铁、锌、镁、铜的测定,比较3组对象的区别并做统计学分析。结果 3组受试者均存在各种微量元素的缺乏,其中以缺钙和镁最为常见。早孕组的锌、钙和镁的含量与正常对照相比差异有统计学意义。晚孕组的铁、钙和镁含量与正常对照相比差异有统计学意义(P<0.05)。结论孕妇在怀孕期必须补充一定量的微量元素,否则会影响胎儿的生长发育,具有一定的临床指导意义。

Objective To investigate the concentrations of trace elements in peripheral blood of pregnant women,and provide valuable information for prenatal care of pregnant women. Methods A total of 250 pregnant women in early pregnancy,median-term pregnancy,late pregnancy,and 100 health controls were recruited in this study to detect the contents of trace elements by BH5100 atomic absorption spectrophotometry,then the results were compared and analyzed by statistics. Results Pregnant women in these three groups exhibited the lack of some trace elements,especially Ca2 ＋and Mg2 ＋. The concentrations of Zn2 ＋,Ca2 ＋and Mg2 ＋showed significant difference between women of early pregnant group and control group,while the concentrations of Fe2 ＋,Ca2 ＋and Mg2 ＋in women of late pregnant group were significantly different with those in control group（P〈0. 05）.Conclusion The pregnant women should be supplied with enough trace elements in early pregnant period,otherwise,it will be harmful to the children. Determination of trace elements in pregnant women has certain directive significance in clinic.