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慢性心力衰竭患者血清Copeptin水平及临床意义 被引量：4

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摘要 目的:研究不同程度心力衰竭及不同性质心力衰竭患者血清和肽素(Copeptin)水平及临床意义。方法:同时测定80名健康者(健康对照组)和130例慢性心力衰竭(CHF)患者(CHF组)的血清Copeptin和N末端脑钠肽(NT-proBNP)水平,并检测左室射血分数(LVEF)和左室舒张末期内径(LVEDd)值、E/A值、E/e'值。CHF组患者再按不同左室射血分数及收缩性心力衰竭(SHF)和舒张性心力衰竭(DHF)分组,比较各组血清Copeptin和NT-proBNP水平。结果:CHF组患者血清Copeptin和NT-proBNP水平明显高于健康对照组(P<0.01),不同程度CHF及不同性质的CHF患者其Copeptin之间比较有统计学意义。结论:Copeptin水平可作为心力衰竭患者临床诊断、评估病情的一个客观指标,有助于鉴别收缩性与舒张性心力衰竭。
作者 高洁 吴萍 徐文俊 张超 车在前
机构地区 上海市嘉定区南翔医院 上海市嘉定区南翔社区卫生服务中心 上海市同济医院 上海交通大学医学院附属瑞金医院北院
出处 《内科急危重症杂志》 2014年第4期262-263,282,共3页 Journal of Critical Care In Internal Medicine
基金 上海市嘉定区科委课题基金(No:201117)
关键词 和肽素 N末端脑钠肽 心力衰竭
分类号 R541.61 [医药卫生—心血管疾病]
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参考文献9

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二级参考文献50

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共引文献900

同被引文献28

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二级引证文献16

内科急危重症杂志
2014年 第4期

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