^(131)I治疗甲状腺功能亢进伴2型糖尿病患者的临床疗效观察

Clinical efficacy observation of ^(131)I in the treatment of patients with hyperthyroidism complicated with type 2 diabetes

目的观察131I治疗105例甲状腺功能亢进伴2型糖尿病患者的临床疗效。方法回顾性分析2011年9月至2013年9月收治的105例甲状腺功能亢进伴2型糖尿病患者的临床资料。结果观察组患者的总有效率为89.1%(49/55),对照组为74%(37/50),差异有统计学意义(P<0.05);治疗后观察组患者的TT3、TT4、FT3、FT4、TSH、FPG、2hPG、HbAlc水平均明显比对照组低(P<0.05);治疗后9、12、24个月观察组患者的甲状腺功能减低发生率及甲状腺功能亢进症复发率均明显比对照组低(P<0.05)。结论131I治疗甲状腺功能亢进伴2型糖尿病患者的临床疗效良好。

Objective To observe the clinical efficacy of^131I on 105 patients with hyperthyroidism complicated with type 2 diabetes. Methods The clinical data of 105 patients with hyperthyroidism complicated with type 2 diabetes admitted in Tangyin people＇s hospital from September 2011 to September 2013 were retrospectively analyzed. Results The total effective rate of the observation group was 89. 1%（ 49 /55）,and was 74%（ 37 /50） of the control group,there was significant difference（ P〈0. 05）. After treatment,the levels of TT3,TT4,FT3,FT4,TSH,FPG,2hPG and HbAlc of the observation group were significantly lower than those of the control group（ P〈0. 05）. After 9,12 and 24 months of treatment,the incidence of hypothyroidism and the relapse rate of hyperthyroidism in the observation group was significantly lower than that in the control group（ P〈0. 05）.Conclusion The clinical efficacy of^131I on patients with hyperthyroidism complicated with type 2 diabetes is good.