自身免疫性胰腺炎诊治进展

Diagnosis and treatment of autoimmune pancreatitis

自身免疫性胰腺炎(AIP)是一种由自身免疫介导、以胰腺肿大及胰管不规则狭窄为特征的胰腺慢性炎症性疾病,病理以胰管纤维化伴有淋巴浆细胞浸润为特征,其治疗尚缺乏统一标准。本文就自身免疫性胰腺炎的流行病学、发病机制、临床特点、影像学检查、病理学特点、诊断标准、治疗及预后七个方面的相关研究进展进行综述,以加深对其认识及了解。

Autoimmune pancreatitis（ AIP） is an autoimmune-mediated chronic inflammatory disease with pancresa tumefaction and pancreatic duct stenosis. Its pathologic examination reveals a characteristic lympho-plasmacytic infiltrate and exhibits interstitial fibrosis and acinar cell atrophy. AIP is lack of widely recognized treatment standard. The objective of this article is to recognize AIP by reviewing its epidemiology,pathogenesis,clinical features,radiologic features,pathology,diagnostic criteria,treatment and prognosis.