2011～2012年我院病原菌分布及耐药性分析

Analysis of pathogenic bacteria distribution and drug resistance from 2011 to 2012 in our hospital

目的:分析我院病原菌分布及耐药情况,为临床医生合理选择抗菌药物提供参考依据,减少或延缓耐药菌的产生。方法:分析我院检验科临床微生物检测数据,并采用K-B纸片扩散法进行药敏试验,以了解病原菌分布及耐药情况。结果:2011年共分离G+病原菌194株,金黄色葡萄球菌分布构成比为35.57%;分离G-病原菌452株,大肠埃希菌分布构成比为27.43%;2012年共分离G+病原菌764株,金黄色葡萄球菌分布构成比为23.2%;分离G-病原菌2130株,大肠埃希菌分布构成比为27.42%。金黄色葡萄球菌对于青霉素、红霉素、苯唑西林的耐药率均超过50.0%,大肠埃希菌对于阿莫西林、头孢噻吩、头孢呋辛、COSMZ、环丙沙星的耐药率均超过50.0%。结论:临床上应根据病原菌的耐药性合理选择抗菌药物,减少和避免细菌耐药性的产生。

Objective： to analyze the 2011 to 2012 in our hospital of pathogen distribution and drug resistance, as the clinical drug references, reduce or delay the drug resistant bacteria. Methods： analysis of 2011 - 2012 Inspection Department of our hospital clinical microbiological detection data, and using the broth microdilution susceptibility test, in order to understand the pathogen distri- bution and drug resistance. Results ： in 2011 were isolated G ＋ 194 strains of pathogenic bacteria, Staphylococcus aureus distribution ratio 35.57% ; G pathogen isolated 452 strains of bacteria, Escherichia coli distribution proportion was 27.43% ; in 2012 a total of 764 strains of pathogenic bacteria isolated from G ＋, Staphylococcus aureus distribution proportion for 23.2% ; separation of G pathogen 2130 strains of Escherichia coli, distribution ratio 27.42%. Staphylococcus aureus was more than 50% for resistance to penicillin, erythromycin, methieillin rate, Escherichia eoli were more than 50% for resistance, cephalothin, cefuroxime, amoxicillin, ciprofloxacin COSMZ. Conclusion： the clinical should be based on selection of antibiotics drug resistance of pathogenic baeteria, reduce and avoid the generation of bacterial resistance.