多囊卵巢综合征的病因、临床及内分泌特征的相关性研究

The Association Study on Etiology, Clinical and Endocrine Features of Polycystic Ovary Syndrome

目的:观察多囊卵巢综合征的病因、临床及内分泌特征性指标,为其下一步临床工作提供一定的借鉴和依据。方法:选择30例多囊卵巢综合征患者为观察组,30例正常育龄妇女为对照组,采用化学发光法测定血清性激素、DHEA-S以及SHBG等指标水平。比较两组BMI、腰围、血清性激素水平、DHEA-S、SHBG以及DBP等指标的差异。结果:两组的月经周期、BMI、腰围等比较差异均有统计学意义(P<0.05);两组的LH、T值以及DHEA-S值比较差异均有统计学意义(P<0.05);两组的胰岛素抵抗相关参数及SHBG、FTI比较差异均有统计学意义(P<0.05)。结论:多囊卵巢综合征在BMI、DHEA-S、SHBG、胰岛素抵抗相关参数及FTI等水平表达具有特征性,特别是胰岛素抵抗相关参数,能够作为诊断多囊卵巢综合征的依据之一。

Objective：To observe the etiology,clinical and endocrine characteristic index of polycystic ovary syndrome,as its next provide certain reference and basis for clinical work. Method：30 patients with polycystic ovary syndrome were selected as the observation group,30 cases of normal women of childbearing age as the control group, the chemiluminescence method for determination of serum sex hormones,and DHEA-S,and SHBG levels. BMI,waist circumference,serum sex hormone levels,DHEA - S,SHBG and DBP and other indicators of the two groups were compared.Result：The menstrual cycle,BMI,waist circumference of the two groups were compare,the differences had statistical significance（P〈0.05）;the LH,T value,and DHEA-S value of the two groups were compared,the differences were statistically significant（P〈0.05）;the related parameters of insulin resistance and SHBG,FTI index were compared between the two groups,the differences had statistical significance（P〈0.05）.Conclusion：Polycystic ovary syndrome in BMI,DHEA-S,SHBG and insulin resistance related parameters and FTI level expression is characterized, especially in insulin resistance parameters,one can be used as the basis for diagnosis of polycystic ovary syndrome.