肺癌肿瘤实性区CT强化程度与肿瘤分期及病理类型的相关性分析

The Correlation Analysis between Lung Cancer Tumor Solid Zone CT Enhancement Degree and Tumor Staging and Pathologic

目的：探讨影响肺癌肿瘤实性区的CT强化程度与肿瘤分期及病理类型的相关性分析。方法：回顾性分析2013年1月-2014年6月本院收治的200例行胸部CT增强扫描肺癌患者的临床资料，统计分析肿瘤实性区的CT强化程度与肿瘤T分期（T1/T2/T3/T4）、病理类型（小细胞癌/鳞癌/腺癌）、神经元特异性烯醇化酶（NSE）的关系。结果：200例肺癌肿瘤实性区的CT强化程度的范围为1.652~4.193，平均（2.529±0.592）。T1期31例、T2期60例、T3期39例、T4期70例，平均CT强化程度分别为（2.145±0.334）、（2.288±0.445）、（2.625±0.589）、（2.767±0.659）。T1和T2、T3和T4之间差异无统计学意义（P〉0.05）；T3和T4明显高于T1和T2，差异均有统计学意义（P〈0.05）。小细胞癌42例、鳞癌58例、腺癌100例，平均CT强化程度分别为（2.208±0.484）、（2.567±0.485）、（2.680±0.641）；鳞癌和腺癌比较差异无统计学意义（P〉0.05），小细胞癌明显低于鳞癌和腺癌，差异有统计学意义（P〈0.05）。NSE水平范围是8.02~109.73 ng/mL，平均（28.423±20.473）ng/mL，经线性相关分析CT强化程度与NSE水平之间无明显相关性（P〉0.05）。结论：随着肿瘤T分期的增高肺癌肿瘤实性区的CT强化程度有逐渐升高的趋势；非小细胞肺癌的CT强化程度高于小细胞肺癌；肺癌肿瘤实性区的CT强化程度与NSE水平无明显相关性。

To investigate the correlation analysis between lung cancer tumor solid zone CT enhancement degree and tumor staging and pathologic.Method：The clinical data of 200 patients with lung cancer underwent chest CT enhancement scanning from January 2013 to June 2014 were retrospectively analyzed,the relationship of the CT enhanced degree of solid area of Lung cancer and the tumor T stage（T1/T2/T3/T4）and pathological types（squamous carcinoma/small cell carcinoma/adenocarcinoma）,neuron specific enolization enzyme（NSE）were analyzed.Result：The range of the CT enhanced degree of 200 cases of lung cancer was 1.652-4.193,the average was （2.529±0.592）.31 cases were T1,60 cases were T2,39 cases were T3,70 cases were T4,the average CT enhanced degree were（2.145±0.334）,（2.288±0.445）,（2.625±0.589）,（2.767±0.659）.There was no statistically significant difference between T1 and T2,T3 and T4（P〉0.05）;T3 and T4 were significantly higher than those of T1 and T2,the differences were statistically significant（P〈0.05）.42 cases were small cell carcinoma,58 cases were squamous carcinoma,100 cases were adenocarcinoma,the average CT enhanced degree were（2.208±0.484）,（2.567±0.485）, （2.680±0.641）.The differences had no statistical significance in squamous carcinoma and adenocarcinoma（P〉0.05）, The small cell carcinoma was significantly lower than the squamous carcinoma and adenocarcinoma,the differences were statistically significant（P〈0.05）.NSE levels range from 8.02 to 109.73 ng/mL,the average was（28.423±20.473）ng/mL, by the linear correlation analysis：CT enhanced degree had no obvious correlation with the level NSE levels（P〉0.05）. Conclusion：CT enhanced degree of solid area of lung cancer has an increased trend as the T staging increased;CT enhanced degree of non-small cell lung cancer is higher than small cell lung cancer;CT enhanced degree has no obvious correlation with the level NSE levels.