检测降钙素原对儿科危重监护病房感染性疾病预后的评估分析

Assessment of Disease Prognosis in Primary Infection in Pediatric ICU of Calcitonin Detection

目的:探讨血清降钙素原检测对儿科危重监护病房感染性疾病的诊断以及预后判断的临床价值。方法:回顾性分析本院儿科在2011年1月-2013年12月收治的120例感染性疾病患儿的临床资料,按照患者不同感染类型,将上述患儿分为两组,其中细菌感染组65例,病毒感染组55例,对所有患儿进行血清降钙素原检查以及细菌血培养检查,并选择同期在本院进行体检的正常儿童50例,对所有儿童的检查结果进行分析。结果:细菌感染组患儿血清降钙素原检测结果为阳性者53例,阳性率为81.54%;病毒感染组患儿血清降钙素原检测结果为阳性者4例,阳性率为7.27%;正常组儿童血清降钙素原检测结果为阳性者为4例,阳性率为8.0%。细菌感染组患儿降钙素原阳性率显著高于病毒感染组和正常组,比较差异均具有统计学意义(t=12.2,P<0.05);病毒感染组患儿降钙素原阳性率与正常组比较差异无统计学意义(t=1.61,P>0.05)。结论:血清降钙素原能够准确地反映患儿感染性疾病的程度,对于患儿疾病的诊断以及预后判断具有良好的临床应用价值,对于患儿疾病的诊断、治疗以及预后评估具有很好的指导意义,值得临床推广。

To investigate the serum procalcitonin detection of clinical value in the diagnosis of pediatric ICU infection disease and prognosis. Method：To retrospectively analyze clinical data of 120 cases with infectious diseases from 2011 January to 2013 December in our hospital,according to patients with different infection types. The patients were divided into two groups,one group contained 65 cases with bacterial infection,viral infection group with 55 cases,the serum procalcitonin and bacterial blood culture inspection of all patients were tested,50 normal children were selected to undergo a medical examination in our hospital,the examination results of all the children were analyzed. Result：Bacterial infection group serum procalcitonin test results were positive in 53 cases,the positive rate was 81.54%;4 cases of viral infection group serum procalcitonin test results were positive,the positive rate was 7.27%;the normal group of children,the serum procalcitonin test results were positive in 4 cases,positive rate of 8%. Procalcitonin positive rate of bacterial infection group was significantly higher than that of group and normal group of virus infection,the differences were statistically significant（t=12.2,P〈0.05）;viral infection group procalcitonin positive rate compared with the normal group had no significant difference（t=1.61,P〉0.05）. Conclusion：The serum procalcitonin can accurately reflect the degree of children with infectious diseases,has a good clinical application value in the diagnosis and prognosis of children with the disease,and has the very good guiding significance for the diagnosis,therapy and prognosis assessment of children with the disease,it is worthy of clinical promotion.