慢性阻塞性肺疾病急性加重危险窗证候分布的临床调查研究

Clinical Investigation on Distribution of Syndrome in AECOPD-RW

目的:基于临床调查阐释慢性阻塞性肺疾病急性加重(AECOPD)危险窗证候分布规律并探讨病机转化。方法:收集8所医院AECOPD患者急性加重缓解后进入危险窗的中医证候学相关资料,建立数据库,运用SPSS 13.0进行统计分析。结果:本次调查结果显示,15个基础证候中以肺气虚证频率最高,其次是肾气虚证和痰湿证;14个复合证候中以肺肾气虚证和痰湿阻肺证出现频率最高;AECOPD危险窗临床常见证候有肺肾气虚兼痰湿阻肺、肺肾气虚、肺脾气虚兼痰湿阻肺、肺脾气虚、肺肾气阴两虚兼痰湿阻肺、肺肾气阴两虚、肺肾气虚兼痰瘀阻肺和肺肾气阴两虚兼痰瘀阻肺。结论:AECOPD危险窗常见证候以虚实夹杂为主,单纯虚证及单纯实证较少。

This article was aimed to explain the distribution of syndrome and study the change of pathogenesis in patients of acute exacerbation of chronic obstructive pulmonary disease risk-window （AECOPD-RW） based on clinical investigation. The data of the traditional Chinese medicine （TCM） syndrome of patients diagnosed as AECOPD into AECOPD-RW were collected from 8 hospitals. The database was established. Data was analyzed with SPSS 13.0 software. The results showed that among 15 basic syndromes, the syndrome of lung-qi deficiency was with the highest frequency, which was followed by the syndrome of kidney-qi deficiency and syndrome of phlegm-dampness. Among 14 combined syndromes, the syndrome of lung-kidney qi deficiency and the syndrome of phlegm-dampness accumulated in the lung were with the highest frequency. The common syndromes of AECOPD-RW were the syndrome of lung-kidney qi deficiency combined with the syndrome of phlegm-dampness accumulated in the lung, the syndrome of lung-kidney qi deficiency, the syndrome of lung-spleen qi deficiency combined with the syndrome of phlegm-dampness accumulated in the lung, the syndrome of lungspleen qi deficiency, the syndrome of lung-kidney qi-yin deficiency combined with the syndrome of phlegm-dampness accumulated in the lung, the syndrome of lung-kidney qi-yin deficiency, the syndrome of lung-kidney qi deficiency combined with the syndrome of phlegm-stasis accumulated in the lung, and the syndrome of lung-kidney qi-yin deficiency combined with the syndrome of phlegm-stasis accumulated in the lung. It was concluded that the main common syndromes of AECOPD-RW was the mixture of deficiency and excess. There was relatively less pure deficiency and excess syndrome.