摘要
目的:探讨电磁脉冲对猕猴凝血机制影响。方法:经高场强电磁脉冲源以6×104V/m全身辐照5只猕猴,于照前及照后1、3、7、14、28及90d下肢前静脉采血,采用AYW-8001型血凝仪检测电磁脉冲对动物血浆中TT、PT、APTT及FIB的影响。结果:动物血浆中TT于伤后1d及14~28d延长,APTT于伤后1d延长,FIB含量于伤后14d减少,PT在照射前后无明显变化。结论:电磁脉冲照射可对实验猕猴凝血机制产生影响,可通过TT、APTT延长和FIB含量减少而使机体凝血机制发生障碍。
Purpose:The aim is to study for EMP influence on the clotting mechanism in monkeys.Methods:5monkeys were irradiated with6×10 4 V/m EMP,the vein blood was abstracted before radiation and1,3,7,14,28and90days respectively after ra diation.By means of AYW-8001Blood Clotting Apparatus,the thrombim time,prothrombin time,active past throm bin time and fibrinogen in plasma were detected.Results:Both TT and APTT were prolonged at1day after injury,APTT was also prolonged in14~28days.The contents of FIB in plasma was decreased at14days after injury.PT in the plasma did not change before and after injury.Conclusion:EMP may influence on the clotting mechanism of monkeys,make the mechanisms ob struct throng making TT and APTT prolong and FIB decrease.
出处
《中国医学物理学杂志》
CSCD
2002年第3期161-162,共2页
Chinese Journal of Medical Physics
基金
全军"十五"医药卫生科研基金指令课题(编号01L023)