期刊文献+

电磁脉冲辐射对猕猴凝血机制影响研究 被引量:3

Studies for electromagnetic pulse(EMP)influence on the clotting mechanism in monkeys
下载PDF
导出
摘要 目的:探讨电磁脉冲对猕猴凝血机制影响。方法:经高场强电磁脉冲源以6×104V/m全身辐照5只猕猴,于照前及照后1、3、7、14、28及90d下肢前静脉采血,采用AYW-8001型血凝仪检测电磁脉冲对动物血浆中TT、PT、APTT及FIB的影响。结果:动物血浆中TT于伤后1d及14~28d延长,APTT于伤后1d延长,FIB含量于伤后14d减少,PT在照射前后无明显变化。结论:电磁脉冲照射可对实验猕猴凝血机制产生影响,可通过TT、APTT延长和FIB含量减少而使机体凝血机制发生障碍。 Purpose:The aim is to study for EMP influence on the clotting mechanism in monkeys.Methods:5monkeys were irradiated with6×10 4 V/m EMP,the vein blood was abstracted before radiation and1,3,7,14,28and90days respectively after ra diation.By means of AYW-8001Blood Clotting Apparatus,the thrombim time,prothrombin time,active past throm bin time and fibrinogen in plasma were detected.Results:Both TT and APTT were prolonged at1day after injury,APTT was also prolonged in14~28days.The contents of FIB in plasma was decreased at14days after injury.PT in the plasma did not change before and after injury.Conclusion:EMP may influence on the clotting mechanism of monkeys,make the mechanisms ob struct throng making TT and APTT prolong and FIB decrease.
出处 《中国医学物理学杂志》 CSCD 2002年第3期161-162,共2页 Chinese Journal of Medical Physics
基金 全军"十五"医药卫生科研基金指令课题(编号01L023)
关键词 电磁脉冲辐射 猕猴 凝血机制 影响研究 electromagnetic pulse monkey clotting mechanism
  • 引文网络
  • 相关文献

参考文献2

二级参考文献9

共引文献90

同被引文献20

  • 1Robert H.Getzenberg.Commentary on: Mobley AJ, Lam YW, Lau KM, Pais VM, Lesperance JO, Steadman B, et al. Monitoring the serological Proteome Colon, the latest modality in prostate cancer detection. J Urol 2004; 172: 331-7.[J].Asian Journal of Andrology,2004,6(4):283-283. 被引量:94
  • 2周娅蕾,罗二平,申广浩,吴小明,谢康宁,闫志伟.脉冲电磁场对大鼠骨髓间充质干细胞增殖及成骨分化的影响[J].第四军医大学学报,2007,28(13):1234-1237. 被引量:6
  • 3Maes A, Van Gorp U, Verschaeve L. Cytogenetic investigation of subjects professionally exposed to radiofrequeney radiation[J]. Mutagenesis, 2006, 21(2): 139-42.
  • 4Asahara T, Murohara T, Sulliven A, et al. Isolation of putative progenitor endothelial cel!s for angiogenesis [J]. Science, 1997, 275(5302): 964-967.
  • 5Michelozzi P, Capon A, Kirchmayer U, et al. Adult and childhood leukemia near a high-power radio station in Rome, Italy[J]. Am J Epidemiol, 2002, 155(12): 1096-103.
  • 6McElroy JA, Egan KM, Titus-Emstoff L, et al. Occupational exposure to electromagnetic field and breast cancer risk in a large, population-based, case-control study in the United States [J]. J Occup Envi- ron Med, 2007, 49(3): 266-274.
  • 7Zhang ZG, Li Z, Quan J, et al. bone marrow-derived endothelial progenitor cells participate in cerebral neovascularization after focal cerebral ischemia in the adult mouse [J]. Cir Research, 2002, 90(3): 284-288.
  • 8Friedrich EB, Walenta K, Scharlau J, et al. CD34-/CD133+/VEGFR-2+endothelial progenitor cell subpopulation with potent vasoregenerative capacities[J]. Cir Res, 2006, 98(3): 20-25.
  • 9Miyamoto M, Yasutake M, Takano H, et al. Therapeutic angiogenesis by autologous bone marrow cell implantation for refractory chronic peripheral arterial disease using assessmcnt of neovascularization by 99mTc-tetrofosmin (TF) perfusion scintigraphy[J]. Cell Trans, 2004, 13(4): 429-437.
  • 10Tateishi YE, Matsubara H, Murohara T, et al. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: A pilot study and a randomised controlled trial[J]. Lancet, 2002, 360(9331): 427-435.

引证文献3

二级引证文献12

;
使用帮助 返回顶部