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表阿霉素联合紫杉醇在局部晚期乳腺癌新辅助化疗中的应用观察 被引量:2

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摘要 目的分析局部晚期乳腺癌新辅助化疗中应用表阿霉素联合紫杉醇治疗的临床疗效。方法局部晚期乳腺癌新辅助化疗患者95例,随机分为两组,对照组47例采取表柔比星、氟尿嘧啶联合环磷酰胺治疗,观察组48例采取表阿霉素联合紫杉醇治疗,对比两组临床疗效及不良反应。结果观察组治疗总有效率89.6%显著高于对照组68.1%,差异有统计学意义(P<0.05),不良反应发生率14.6%显著低于对照组29.8%,差异有统计学意义(P<0.05)。结论表阿霉素联合紫杉醇在局部晚期乳腺癌新辅助化疗中具有较高临床应用价值,可有效改善患者临床症状,大幅提高其生存质量,治疗安全性高且患者耐受性良好,值得在临床中推广。
作者 武阳
出处 《中国实用医药》 2014年第24期155-156,共2页 China Practical Medicine
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