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A PGD Pregnancy Achieved by Embryo Copy Number Variation Sequencing with Confirmation by Non-Invasive Prenatal Diagnosis 被引量:3

A PGD Pregnancy Achieved by Embryo Copy Number Variation Sequencing with Confirmation by Non-Invasive Prenatal Diagnosis
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摘要 Aneuploidy rates in embryos produced by assisted reproduc- tive technologies commonly exceed 50%, particularly in couples where the woman is of advanced maternal age or has experienced repeated implantation failure (Harper et al., 2012). Pre-implantation genetic diagnosis (PGD) conducted at many fertility clinics worldwide is now a frontline treatment for infertile couples with a poor prognosis for pregnancy as well as couples where one partner is a carrier of a balanced translocation (Munne, 2012). Aneuploidy rates in embryos produced by assisted reproduc- tive technologies commonly exceed 50%, particularly in couples where the woman is of advanced maternal age or has experienced repeated implantation failure (Harper et al., 2012). Pre-implantation genetic diagnosis (PGD) conducted at many fertility clinics worldwide is now a frontline treatment for infertile couples with a poor prognosis for pregnancy as well as couples where one partner is a carrier of a balanced translocation (Munne, 2012).
出处 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2014年第8期453-456,共4页 遗传学报(英文版)
关键词 PGD CNVs IVF
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