我院2013年麻醉性镇痛药临床应用分析Δ

Analysis of Clinical Application of Narcotic Analgesic Drugs in Our Hospital in 2013

目的:调查分析临床麻醉性镇痛药的应用情况,促进合理用药。方法:统计2013年我院麻醉性镇痛药应用情况,包括使用量、销售金额、使用科室及用途等,同时进行处方点评,分析用药合理性。结果:我院以硫酸吗啡缓释片、枸橼酸芬太尼注射液、盐酸布桂嗪注射液用药频度(DDDs)最大。芬太尼注射液及盐酸布桂嗪注射液主要用于手术镇痛;硫酸吗啡缓释片则主要用于癌症等中重度疼痛患者的口服止痛。多数药物销售金额/DDDs排序比接近于1,表示同步性良好。麻醉性镇痛药的主要用途是手术麻醉辅助用药及术后镇痛、癌症镇痛、普通外伤镇痛等。使用科室主要以外科、肿瘤科、妇产科、急诊科为主。在用药合理性方面,用药剂量、频次等方面仍存在问题,还需改进。结论:对于癌痛患者的镇痛治疗,还需临床医师严格按照《癌症三阶梯止痛指导原则》使用麻醉性镇痛药,提高用药合理性。

OBJECTIVE： To investigate and analyze the application of narcotic analgesic drugs, and to promote rational use of drugs. METHODS： The application of narcotic analgesic drugs in our hospital in 2013 was analyzed statistically in respects of quantity, amount, clinical departments and purpose, etc. The rationality of drug use were analyzed by prescription comment simultaneously. RESULTS： DDDs of Morphine sulfate sustained-release tablets, Fentanyl citrate injection and Bucinnazine hydrochloride injection were the largest in our hospital. Fentanyl injection and Bucinnazine injection were mainly used for surgery analgesia; Morphine sulfate sustained-release tablet was mainly used for cancer patients with moderate or severe pain. Most of drug amount/DDDs sequencing ratio was close to 1, which meant that synchronization was good. The purpose of narcotic analgesic drugs was mainly for auxiliary drug anesthesia, postoperative analgesia, cancer analgesia and common trauma analgesia, etc. The drugs were mainly used in surgery department, oncology department, gynecology and obstetrics department, emergency department. In terms of drug use rationality, the dosage and frequency of narcotic analgesic drugs still needed to be improved. CONCLUSIONS： For analgesics therapy, the clinicians need use the narcotic analgesic drugs in strictly accordance with Cancer 3 Level Analgesic Ladder Therapy Guidelines and improve the rationality of drug use.