强力增智饮治疗卒中后轻度认知功能障碍30例疗效观察

Treatment of mild cognitive function impairment after stroke with Qianglizengzhi drink

目的观察强力增智饮治疗卒中后轻度认知功障碍的临床疗效。方法将60例卒中后轻度认知功障碍患者随机分为2组,对照组30例在常规治疗基础上予尼莫地平片口服治疗,治疗组30例在对照组基础上予强力增智饮口服。2组共治疗3个月,治疗前后分别采用简易智能状态量表(MMSE)及蒙特利尔认知评估量表(MoCA)对患者进行评估,并观察患者各证候评分变化,比较2组临床疗效。结果 2组治疗后MMSE、MoCA评分较本组治疗前均升高(P<0.05),且治疗组升高更明显(P<0.05)。治疗组治疗后各临床症状均明显改善(P<0.05),且腰膝痠软、倦怠思卧、头晕、耳鸣、头痛如刺或固定不移、舌质紫黯及脉沉细等改善情况优于对照组(P<0.05)。对照组治疗后仅健忘及头晕、耳鸣方面较治疗前改善明显(P<0.05),其余各项均无明显改善(P>0.05)。治疗组总有效率93.33%,对照组70.00%,2组比较差异有统计学意义(P<0.05)。结论强力增智饮治疗卒中后轻度认知功障碍疗效确切,值得临床推广。

Objective To observe the effect of mild cognitive function impairment after stroke treated by Qianglizengzhi drink .Methods 60 patients with mild cognitive function impairment after stroke were randomly di-vided into two groups .30 cases in control group were treated by nimodipine on the basis of conventional therapy .30 cases in treatment group were treated by Qianglizengzhi drink on the basis of control group treatment .The course was three months in two groups.The effect was evaluated by adopting MMSE , MoCA and observation of syndrome score changes.Results MMSE and MoCA after treatment were increased as compared with those before treatment in two groups （ P〈0.05）.The increase in treatment group was more obvious （ P 〈0.05）.The total effective rate in treat-ment group （93.33%） was higher than that in control group （70.00%, P 〈0.05）.Conclusion The curative effect of Qianglizengzhi drink on the treatment of mild cognitive function impairment after stroke is definite and worth clinical promotion .