脑卒中后焦虑患者健康相关生存质量及其相关因素

Health-related quality of life and its related factors in patients with post-stroke anxiety

目的:探讨脑卒中后焦虑(PSA)患者健康相关生存质量(HRQOL)及其相关因素。方法:对317例不同临床类型缺血性脑卒中患者进行临床神经功能缺损程度、脑卒中专门化生存质量量表(SS-QOL)评分,对符合PSA诊断的患者进行Hamilton焦虑量表评分;分析与HRQOL相关的因素。结果:PSA发生率为45.11%(143例);不同卒中类型患者PSA发生率差异无统计学意义,SS-QOL评分由低到高依次为完全前循环梗死型、部分前循环梗死型、后循环梗死型及腔隙性梗死型,各型间差异有统计学意义(P<0.05)。除语言因子外,PSA组SS-QOL总分及其他各因子明显低非PSA组(P<0.05或0.01);焦虑程度重、女性、<60岁、未婚或丧偶、高中以上文化程度、家庭月收入<2000元、神经功能缺损程度重和住院期间由护工照顾与HRQOL呈相关性。结论:PSA发生率较高,性别、年龄、婚姻状况、文化程度、家庭月收入、神经功能缺损程度、照顾者及焦虑程度是影响PSA患者HRQOL的因素。

To investigate the health-related quality of life（HRQOL）and its influence fac-tors in patients with post-stroke anxiety（PSA）. Method：Three hundred and seventeen patients with differ-ent clinical types ischemic stroke were assessed by the egree of clinical neural function defect scale and stroke-specific quality of life（SS-QOL）scale. The patients conformed PSA diagnostic criteria were evaluated by Ham-ilton anxiety scale. The associated factors of HRQOL were analyzed. Results：The PSA incidence among those patients was 45. 11＆#177;（143 cases）,which among the different types of stroke was not significantly different. The scores from low to high were anterior circulation infarct,partial anterior circulation infarct,posterior circulation infarction and lacunar infarction and which had significant differences among the different types of stroke（P ﹤0. 05）. In addition to the language factor,total score and each factor score of SS-QOL in PSA patients were sig-nificantly lower than those inpatients with non-PSA（P ﹤ 0. 05 or P ﹤ 0. 01）. The severe anxiety,female,﹤ 60 years old,unmarried or widowed,high school or higher education level,family income ﹤ 2000 yuan/ month,se-vere degree of neurological impairment,with workers care during hospitalization were the negative factors of HRQOL for the PSA patients. Conclusion：The PSA incidence is higher in patients with ischemic stroke. Gender,age,marital status,education level,family income,degree of neurological deficit,carers and anxiety are the influence factors of HRQOL in PSA patients.