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一例SAPHO综合征患者的护理

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摘要 SAPHO综合征由Chmot等[1]在1987年首次提出,包括滑膜炎(synovitis)、痤疮(acne)、脓疱疮(pustucosis)、骨肥厚(hyperostosis)、骨炎(osteistis)等一组疾病综合征,简称为SAPHO综合征.临床上患者有皮肤的病变和骨关节病变.皮肤的病变表现掌跖脓疱病、脓疱型银屑病、聚合性痤疮,骨关节的病变表现为骨肥厚、硬化和关节炎.SAPHO综合征是在一定基因背景下的天然免疫异常性疾病[2].该病多为欧、美、日国家报道,国内报道较少.
作者 李岩
出处 《天津护理》 2014年第4期349-350,共2页 Tianjin Journal of Nursing
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  • 1Chamot A,Benhamou CL,Kahn MF, et al. Acne-pustulosis-hyperostosis-osteitis syndrome. Results of a national survey. 85 cases[J]. Rev Rhum Mal Osteoartic, 1987, 54(3): 187-196.
  • 2Kahn MF, Khan MA. The SAPHO Syndrome[J]. Baillieres Clin Rheumatol, 1994, 8(2): 333-362.
  • 3Hurtado-Nedelee M, Chollet-Martin S, Nieaise-Roland P, et al. Characterization of the immune response in the synovitis, acne, pustulosis, hyperostosis,osteitis (SAPHO) syndrome[J]. Rheumatology (Oxford), 2008, 47(8): 1160-1167.
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  • 5Hayem G, Bouchaud-Chabot A, Benali K, et al. SAPHO syndrome: a long-term follow-up study of 120 cases [J]. Semin Arthritis Rheum, 1999, 29(3): 159-171.
  • 6Davies AM, Marino AJ, Evans N, et al. SAPHO syndrome: 20- year follow-up[J]. Skeletal Radiol, 1999, 28 (3): 159-162.
  • 7Wagner AD, Andresen J, Jendro MC, et al, Sustained response to tumor necrosis factor alpha-blocking agents in two patients with SAPHO syndrome[J]. Arthritis Rheum, 2002, 46(7): 1965.
  • 8Huber CE,Judex AG,Freyschmidt J. Sequential combination therapy leading to sustained remission in a patient with SAPHO syndrome[J].Open Rheumatol J,2009,(01):18-21.
  • 9Magrey M,Khan MA. New insights into synovitis,acne,pustulosis hyperostosis and osteitis (SAPHO) syndrome[J].Current Rheumatology Reports,2009,(05):329-333.
  • 10Colina M,Govoni M,Orzincolo C. Clinical and radiologic evolution of synovitis,acne,pustulosis,hyperostosis and osteitis syndrome:a single center study of a cohort of 71 subjects[J].Arthritis and Rheumatism,2009,(06):813-821.

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